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  Indian J Med Microbiol
 

Figure 4: Histological study of pretreatment with chitosan-Pinus merkusii extract nanoparticle on lead acetate-induced nephrotoxicity. Normal morphology of liver sections in the negative control group (a). The lead acetate treated group showed necrosis (indicated by black arrows) (b). Rats treated with chitosan-Pinus merkusii extract nanoparticle 150 mg/kg BW and 300 mg/kg BW showed necrotic changes (c and d). Rats treated with chitosan-Pinus merkusii extract nanoparticle 600 mg/kg showed regeneration in hepatic cells damage (e). H and E ×400

Figure 4: Histological study of pretreatment with chitosan-<i>Pinus merkusii</i> extract nanoparticle on lead acetate-induced nephrotoxicity. Normal morphology of liver sections in the negative control group (a). The lead acetate treated group showed necrosis (indicated by black arrows) (b). Rats treated with chitosan-<i>Pinus merkusii</i> extract nanoparticle 150 mg/kg BW and 300 mg/kg BW showed necrotic changes (c and d). Rats treated with chitosan-<i>Pinus merkusii</i> extract nanoparticle 600 mg/kg showed regeneration in hepatic cells damage (e). H and E ×400