Journal of Advanced Pharmaceutical Technology & Research

REVIEW ARTICLE
Year
: 2021  |  Volume : 12  |  Issue : 4  |  Page : 327--334

Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent


Yasmiwar Susilawati1, Anis Yohana Chaerunisa2, Hesti Purwaningsih1 
1 Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, Indonesia
2 Pharmaceutical and Technology Pharmaceutics, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, Indonesia

Correspondence Address:
Dr. Yasmiwar Susilawati
Department of Biology Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java
Indonesia

Plants have been used as traditional medicine since ancient times for treating the diseases, metabolite active compounds from plants have excellent bioactivity, and pharmacological properties from plants are used as skin whitening agent and antioxidant in multiple mechanisms of action. However, these compounds have physicochemical limitations in terms of its poor solubility and penetration into the cells membrane. Phytosome drug delivery system can be the primary choice to improve the physicochemical properties, which allows increasing the effectiveness. This review aimed to summarize and discuss the phytosome formulations of potential active compounds as skin whitening agent and skin antioxidant, which obtained from Scopus, PubMed, and Google Scholar databases. We assessed that the main purpose of these phytosome formulations was to improve penetration, stability, and solubility of the active compounds. These studies proved that phytosome formulations can improve the physicochemical characteristics and effectiveness of compounds. The phytosome drug delivery system becomes a promising modification technique for natural compounds due to the ability to improve the physicochemical properties and increase the effectiveness. Phytosome formulation could be the excellent approach for cosmeceutical product with good effectivity in the future.


How to cite this article:
Susilawati Y, Chaerunisa AY, Purwaningsih H. Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent.J Adv Pharm Technol Res 2021;12:327-334


How to cite this URL:
Susilawati Y, Chaerunisa AY, Purwaningsih H. Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent. J Adv Pharm Technol Res [serial online] 2021 [cited 2021 Dec 4 ];12:327-334
Available from: https://www.japtr.org/article.asp?issn=2231-4040;year=2021;volume=12;issue=4;spage=327;epage=334;aulast=Susilawati;type=0