Journal of Advanced Pharmaceutical Technology & Research

ORIGINAL ARTICLE
Year
: 2011  |  Volume : 2  |  Issue : 1  |  Page : 43--46

Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity


T Panneerselvam 
 Department of Pharmaceutical Chemistry, Srinivas College of Pharmacy, Valachil, Mangalore, Karnataka, India

Correspondence Address:
T Panneerselvam
Department of Pharmaceutical Chemistry, Srinivas College of Pharmacy, Valachil, Mangalore- 574143, Karnataka
India

A number of 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines 6a-f derivatives were synthesized and their antihyperglycemic activity was evaluated by streptozotocin (STZ) and sucrose-loaded model. Many of oxazolidine derivatives as well as their corresponding substituted phenylhydrazine showed significant reduction in blood glucose level in STZ and sucrose-loaded rat models.


How to cite this article:
Panneerselvam T. Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity.J Adv Pharm Technol Res 2011;2:43-46


How to cite this URL:
Panneerselvam T. Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity. J Adv Pharm Technol Res [serial online] 2011 [cited 2022 Jul 3 ];2:43-46
Available from: https://www.japtr.org/article.asp?issn=2231-4040;year=2011;volume=2;issue=1;spage=43;epage=46;aulast=Panneerselvam;type=0