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ORIGINAL ARTICLE
Year : 2022  |  Volume : 13  |  Issue : 4  |  Page : 312-316

Phytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice)


1 Department of Cosmetic Science, Faculty of Science and Technology, Suan Dusit University, Nakhon Pathom, Thailand
2 Agricultural and Functional Food Processing (AFP), Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi, Bangkok, Thailand
3 Institute of Nutrition, Mahidol University, Nakhon Pathom, Thailand

Correspondence Address:
Asst. Prof. Rittipun Rungruang
Department of Cosmetic Science, Faculty of Science and Technology, Suan Dusit University, 295 Nakhon Ratchasima Road, Dusit District, Bangkok, 10300
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/japtr.japtr_458_22

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The objective of this research was to explore the phytochemicals in Tubtim Chumphae rice bran and determine their potential antioxidant and anticancer activities. The rice bran extract contained total phenolics, flavonoids, and anthocyanins as the major compounds. In addition, it exhibited the highest DPPH, followed by ABTS+, and FRAP radical scavenging activity. Moreover, the cytotoxic effect of the extract on Hep G2, SW620, KATO-III, BT474, and ChaGo-K-1 cancer cell lines was investigated; the obtained IC50 values were 144.6 ± 0.39, 116.9 ± 0.68, 99.6 ± 0.10, 94.4 ± 0.33, and 25.6 ± 0.45 μg/mL, respectively. Overall, the abovementioned results suggest that rice bran extract has potent anticancer activity owing to the induction of cell death in cancer cell lines.


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