Home  |  About JAPTR |  Editorial board  |  Search |  Ahead of print  |  Current issue  |  Archives |  Submit article  |  Instructions  |  Subscribe  |  Advertise  |  Contacts  |Login 
Users Online: 647   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Year : 2022  |  Volume : 13  |  Issue : 2  |  Page : 106-110

Antidiabetic and antihyperlipidemic effects of Premna spinosa bark in experimental animal models

1 Indira Gandhi Institute of Pharmaceutical Sciences, Bhubaneswar, Odisha, India
2 Gracious College of Pharmacy, Raipur, Chhatisgarh, India
3 Tetri Chandravansi Pharmacy College, Nawadihkala, Bisrampur, Palamu, Jharkhand, India
4 Centurion University of Technology and Management, Bhubaneswar, Odisha, India
5 West Bengal Medical Services Corporation Ltd., Salt Lake City, Kolkata, West Bengal, India
6 School of Pharmaceutical Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha, India

Correspondence Address:
Dr. Biswakanth Kar
School of Pharmaceutical Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar - 751 030, Odisha
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/japtr.japtr_300_21

Rights and Permissions

The purpose of the study is to evaluate the antidiabetic and hyperlipidemic potential of stem bark extract of Premna spinosa (Lamiaceae), by using streptozotocin (STZ)-nicotinamide (NA)-induced diabetic and triton-induced hyperlipidemic models in albino rats. The blood glucose, total cholesterol, and triglyceride levels were determined in STZ-NA-induced diabetic and triton-induced hyperlipidemic rats, as per the respective protocols. It was found that there is the dose dependent and significant reduction in foregoing parameters on the administration of extract from Premna spinosa stem bark at the doses of 200, 400, and 800 mg/kg body weight to diabetic and hyperlipidemic rats. From these observed results it may be inferred that the stem bark of Premna spinosa possesses remarkable antidiabetic and antihyperlipidemic properties.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded171    
    Comments [Add]    

Recommend this journal