Home  |  About JAPTR |  Editorial board  |  Search |  Ahead of print  |  Current issue  |  Archives |  Submit article  |  Instructions  |  Subscribe  |  Advertise  |  Contacts  |Login 
Users Online: 2431   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
     
ORIGINAL ARTICLE
Year : 2021  |  Volume : 12  |  Issue : 1  |  Page : 94-98

Modification of Anti-acne Bawang Dayak (Eleutherine bulbosa (Mill.)Urb.) Cream to Propionibacterium acnes


Department of Pharmacy, Faculty of Health Science and Muhammadiyah University of Palangkaraya, Palangka Raya, Indonesia

Correspondence Address:
Ms. Syahrida Dian Ardhany
Jl. RTA Milono km 1,5 Palangka Raya 73111
Indonesia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/japtr.JAPTR_107_20

Rights and Permissions

Bawang dayak is one of the traditional medicines in Central Kalimantan, used to treat acne vulgaris. Previous research reported that a cream made with bawang dayak extract's active ingredient could inhibit Propionibacterium acnes' growth. However, bawang dayak has a pungent odor that causes discomfort, where the cream separates after 3 days of storage, which decreases its potency. This study aims to improve the quality of the anti-acne cream formulation of bawang dayak extract from previous studies with the addition of cinnamon, honey, and peppermint. The modified formula of bawang dayak extract cream was evaluated and tested for its antibacterial activity in vitro. The results showed an increase in the organoleptic test, especially the smell, which gave a more comfortable fragrance than the previous formula. The pH measurement of the cream shows the results suitable for topical applications. However, the homogeneity observations show that all the formulas are homogeneous, seen from uniform colors but contain coarse grains. The antibacterial activity test of all cream formulations against P. acnes showed inhibition zone diameter between 14.85 and 17.10 mm, all of which were moderate and larger than previous studies. It can be concluded that the modification of the cream formula with the active ingredient of bawang dayak extract showed an increase in the inhibition zone against P. acnes and improved organoleptic properties.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed568    
    Printed6    
    Emailed0    
    PDF Downloaded142    
    Comments [Add]    

Recommend this journal