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| EDITORIAL |
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| Year : 2018 | Volume
: 9
| Issue : 4 | Page : 119 |
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Natural products-based nanomedicine
Upendra Nagaich
Editor, Journal of Advanced Pharmaceutical, Technology and Research, Editor-in-Chief, SPER Times, Secretary, Society of Pharmaceutical Education and Research, 22-C, Jawahar Colony, Gwalior - 474 001, Madhya Pradesh, India
| Date of Web Publication | 10-Dec-2018 |
Correspondence Address:
Dr. Upendra Nagaich
Editor, Journal of Advanced Pharmaceutical, Technology and Research, Editor-in-Chief, SPER Times, Secretary, Society of Pharmaceutical Education and Research, 22-C, Jawahar Colony, Gwalior - 474 001, Madhya Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/japtr.JAPTR_374_18
How to cite this article:
Nagaich U. Natural products-based nanomedicine. J Adv Pharm Technol Res 2018;9:119 |
Dear Friends,
Since ancient times, natural products or their derivatives isolated from plants have been used as herbal medicines for the therapy of a variety of diseases. Earlier, when synthetic compounds were not discovered, these crude herbs or their extracts have been used for the cure of many diseases. The challenges associated with these herbal remedies were poor absorption and low bioavailability as seen with curcumin only. The revolution brought about by nanotechnology has been a big boon for these herbal drugs. Nanomaterials namely polymeric nanoparticles, lipoidal nanoparticles, and metallic nanoparticles range <100 nm have unique properties such as high surface area to volume ratio, optical properties making them suitable for diagnosis and therapy, enhances drug stability and liver toxification. Thus, nano-based herbal drug delivery aided in better bioavailability with reduced adverse/side effects. Many natural products-based nanomedicines are available in market, namely Cuscuta chinensis nanoparticles, artemisinin nanocapsules, and berberine-loaded nanoparticles. In addition, natural product-based cosmetic formulations have also been effectively launched in market such as hair care products and sunscreens. Still, today's requirement with these natural product-based nanomedicines is the establishment of the standard analytical profile of herbal marker compounds and costing associated with their extraction and isolation procedure. Apart from this, nanoparticles have been associated with the toxicity issues as these can cross the biological/cellular membranes. Special attention must be focused on the materials/excipients used for the formulation of nanoparticles as their bioaccumulation may further lead to severe toxicity issues.
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