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ORIGINAL ARTICLE
Year : 2010  |  Volume : 1  |  Issue : 2  |  Page : 253-259

Studies on some physicochemical properties of Leucaena Leucocephala bark gum


1 Siddharth Institute of Pharmacy, Sattenapalli, Andhra Pradesh, India
2 Faculty of Pharmacy, 7th April University, Zawia, Libya
3 Department of Chemistry, JNTUA, Anantapur, Andhra Pradesh, India

Correspondence Address:
Vijetha Pendyala
Siddharth Institute of Pharmacy, Sattenapalli, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


PMID: 22247853

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Gum exudates from Leucaena Leucocephala (Family: Fabaceae) plants grown all over India were investigated for its physicochemical properties such as pH, swelling capacity and viscosities at different temperatures using standard methods. Leucaena Leucocephala bark gum appeared to be colorless to reddish brown translucent tears. 5 % w/v mucilage has pH of 7.5 at 28°C. The gum is slightly soluble in water and practically insoluble in ethanol, acetone and chloroform. It swells to about 5 times its original weight in water. A 5 %w/ v mucilage concentration gave a viscosity value which was unaffected at temperature ranges (28-40°C). At concentrations of 2 and 5 %w/v, the gum exhibited pseudo plastic flow pattern while at 10 %w/v concentration the flow behaviour was thixotropic. The results indicate that the swelling ability of Leucaena Leucocephala (LL) bark gum may provide potentials for its use as a disintegrant in tablet formulation, as a hydro gel in modified release dosage forms and the rheological flow properties may also provide potentials for its use as suspending and emulsifying agents owing to its pseudo plastic and thixotropic flow patterns.


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