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REVIEW ARTICLE
Year : 2010  |  Volume : 1  |  Issue : 3  |  Page : 283-290

Microsponges: A novel strategy for drug delivery system


1 Department of Pharmaceutics, Gupta College of Technological Sciences, Ashram More, G.T.Road, Asansol-713 301, West Bengal, India
2 Department of Pharmaceutics, College of Pharmacy, Institute of Foreign Trade and Management, Lodhipur Rajput, Delhi Road, Moradabad - 244 001, Uttar Pradesh, India
3 Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi - 835 215, Jharkhand, India

Correspondence Address:
Santanu Kaity
Department of Pharmaceutics,Gupta College of Technological Sciences, Ashram More, G.T. Road, Asansol - 713 301, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0110-5558.72416

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Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce side effects and modify drug release favorably. Microsponge technology has many favorable characteristics, which make it a versatile drug delivery vehicle. Microsponge Systems are based on microscopic, polymer-based microspheres that can suspend or entrap a wide variety of substances, and can then be incorporated into a formulated product such as a gel, cream, liquid or powder. The outer surface is typically porous, allowing a sustained flow of substances out of the sphere. Microsponges are porous, polymeric microspheres that are used mostly for topical use and have recently been used for oral administration. Microsponges are designed to deliver a pharmaceutical active ingredient efficiently at the minimum dose and also to enhance stability, reduce side effects, and modify drug release.


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